![]() The pathology associated with the infection consists of two stages: an acute phase (the first 2–3 weeks of infection) characterized by high parasitemia and a chronic phase (10–30 years after infection) defined by low parasitemia and syndromes mostly associated with heart failure, megacolon, and megaesophagus. No vaccine has been developed for this infection, and the two drugs available to treat it are of limited use and may present severe secondary effects. Trypanosoma cruzi is the etiological agent of American trypanosomiasis, also known as Chagas disease. Funder full name: Consejo Nacional de Ciencia y Tecnología URL: The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Ĭompeting interests: The authors have declared that no competing interests exist. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.ĭata Availability: All relevant data are within the paper and its Supporting Information files.įunding: CAFL: received a grant of Problemas Nacionales, CONACYT, Mexico. ![]() ![]() Received: Accepted: JPublished: August 4, 2020Ĭopyright: © 2020 Rivas-García et al. PLoS ONE 15(8):Įditor: Ruslan Kalendar, University of Helsinki, FINLAND Citation: Rivas-García L, Carballo-Amador MA, Flores-López CA (2020) Design of a AFLP-PCR and PCR-RFLP test that identify the majority of discrete typing units of Trypanosoma cruzi.
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